A gathering for mice !

Since 2010 One Voice has campaigned for mice killed in large numbers in laboratories (see the history of its actions for the abolition of animal experimentation). The case of those sacrificed for the production of botulinum toxin is particularly cruel. The LD50 (or median lethal dose) test is performed for each batch of toxin to determine the dose that will kill 50% of the mice. The substance is injected into the abdomen, causing them intolerable suffering. Gradually paralyzed, they finally die by suffocation.

In 2011 the Allergan laboratory, the American manufacturer of Botox®, announced that it had found an in vitro method for the development of its product, signing a first victory for the European campaign led by the ECEAE, of which One Voice is the representative for France. Its direct competitors, IPSEN and Merz, have recently followed suit, although validation procedures are still in progress. Only a Japanese firm is still reluctant to give up using mice ...

Eisai is a Japanese laboratory. It sells in Europe Neurobloc®, a botulinum toxin type B drug. Initially intended for the treatment of torticollis, its use is spreading today among those whose wrinkles have become resistant to botulinum toxin type A the competition ... According to our sources, the German laboratory LPT, which carries out the tests for its account in Europe, was authorized to carry out the LD50 on 60,000 mice in 2014! And if Eisai declares that a replacement procedure is being studied, how many will still be tortured before the final analysis? Let's mobilize for an immediate stop of the sacrifice of these mice !

Action for the mice

One Voice and Doctors against Animal Experiments, its German partner in the ECEAE, launches a pressure campaign on Eisai.

• Write to their representative in France !

laboratoire@eisai.net

Or

Eisai SAS

5/6, Place de l'Iris

Manhattan Tower

92095 La Defense

France

You will find below the text we recommend you to use:

Dear Sir or Madam,

I am horrified to learn that your firm is commissioning the LPT contract laboratory to do tests using LD50 your NeuroBloc® product with botulinum toxin B. In 2014, no less than 60,000 mice have been killed!

Other manufacturers have already abandoned animal testing in favour of methods using human cells.

Therefore, I ask you to immediately stop the LD50 tests on mice and replace it with an ethical alternative, one without animals.

Regards,

Name_________________________

Address________________________

• Support the actions of One Voice for the abolition of animal experimentation !